Pantoprazole: Long-term therapy may lead to bacterial overgrowth in GI. Not recommended in childn <12 yr. Domperidone: Galactorrhoea (females) & gynaecomastia (males).
Pantoprazole: May interfere absorption of ketoconazole, ampicillin esters & Fe salts. Domperidone: Inhibited antidyspeptic effect w/ anticholinergics. May suppress peripheral effects of dopaminergic agonist. May influence absorption of drugs w/ SR or EC formulations. May interfere w/ other hypoprolactinaemic agents & some diagnostic tests. Reduced bioavailability w/ antacids & antisecretory agents.
A02BC02 - pantoprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).